April 6-7, 2017 | Lincoln, Nebraska
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2017 NRIC speakers
portrait of Lloyd Sumner

 


Dr. Lloyd Sumner
University of Missouri
Integrated Metabolomics for Deciphering Metabolic Pathways and Emerging Solutions for Addressing the Grand Challenges of Metabolomics
10:30 - 11:00 am, Friday 7 April 2017
ABSTRACT:
This presentation will first describe our metabolomics platform and how we are using metabolomics, correlated gene expression profiling and genome wide association studies (GWAS) for the discovery and characterization of novel saponin biosynthetic genes in the model legume Medicago truncatula. The presentation will also describe a new Plant Metabolite Annotation Toolbox (PlantMAT) for the large-scale prediction of metabolite identity using experimental xC-MS/MS and custom combinatorial databases. The presentation will then describe a sophisticated UHPLC-MS-SPE-NMR approach for automated purification and higher-throughput empirical metabolite identification. The combination of computational and empirical identification has been very successful in the identification of specialized metabolites.
BIO:
Lloyd Sumner acquired his Ph.D. in analytical chemistry from Oklahoma State University in 1993. He joined the Samuel Roberts Noble Foundation in 1999 and rose to the rank of Professor within the Plant Biology Division. He moved to the University of Missouri, Columbia in January 2016 as a professor in the Biochemistry Department and director of the University of Missouri’s Metabolomics Center. Dr. Sumner’s research program focuses upon the development, integration, and application of large-scale biochemical profiling technologies (i.e. metabolomics, proteomics and transcriptomics) for the discovery and characterization of the molecular and biochemical components related to plant specialized metabolism.