April 6-7, 2017 | Lincoln, Nebraska
nsf logo link
2017 NRIC speakers
portrait of Hirsch


Candice Hirsch
University of Minnesota
Understanding variation that persists in the genome of elite maize inbred lines
10:45 - 11:15am, Thursday 6 April 2017
Maize is a species with extensive diversity from the genome to the phenome, and as such is an excellent model system to study natural variation and the relationship between various levels of natural variation such as the genome versus the transcriptome. We recently developed a second maize genome assembly to compliment the existing B73 reference genome assembly. Using these assemblies and transcriptome profiling throughout development we have been able to extensively mine the variation that exists between elite inbred lines at the genome and transcriptome levels. The relationship and impact of promoter variation, transcribed allelic variation, structural variation, and spatial and temporal transcriptional variation will be discussed.
Candy Hirsch is an assistant professor in the Department of Agronomy and Plant Genetics at the University of Minnesota, where she focuses on maize translational genomics.  She received her BS in Genetics and PhD in Plant Breeding and Plant Genetics from the University of Wisconsin-Madison and did her post-doc at Michigan State University. Her research involves the integration of big data including high throughput genome and transcriptome sequencing, high throughput phenotyping, and extensive environmental measurements with the end goal of improving corn as a crop plant. She and her team have projects in the lab examining the maize pan genome including dissecting natural mechanisms that create genome content variation and the impacts on phenotypic variation. She’s also interested in understanding the interaction of genotype and environment and the impact on plant performance and elucidating the molecular mechanisms underlying heterosis in maize.